Prevention of acute mastoiditis: fact or fiction?

Acute mastoiditis is the most common complication of acute otitis media (AO M). In recent years routine antibiotic treatment for acute middle ear infec tions was questioned and even abandoned in some countries. The goal of our study was to investigate the influence of antibiotic treatment on the occur rence and clinical outcome of acute mastoiditis and to analyze the bacterio logical findings. A retrospective case record study of 48 patients with 50 episodes of acute mastoiditis hospitalized at our tertiary-care center betw een 1992 and 1999 was performed. Twenty-three patients (48%) received antib iotic treatment before admission whereas 25 (52%) did not. The group of pat ients without antibiotic pretreatment were younger (mean, 6 years) than pat ients with antibiotics (mean, 18 years) and their referral was delayed. The most common isolated single pathogen was Streptococcus pneumoniae. All pne umococci were sensitive to penicillin. Acute mastoiditis may be the first c linical sign of a middle ear infection, especially in very young children. Adequate antibiotic pretreatment cannot invariably prevent the development of acute mastoiditis even in the absence of penicillin resistant pathogens. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.