Purpose: A geometrically based method of multiple isocenter linear accelera
tor radiosurgery treatment planning optimization,vas developed, based on a
target's solid shape.
Methods and Materials: Our method uses an edge detection process to determi
ne the optimal sphere packing arrangement with which to cover the planning
target. The sphere packing arrangement is converted into a radiosurgery tre
atment plan by substituting the isocenter locations and collimator sizes fo
r the spheres.
Results: This method is demonstrated on a set of 5 irregularly shaped phant
om targets, as well as a set of 10 clinical example cases ranging from simp
le to very complex in planning difficulty. Using a prototype implementation
of the method and standard dosimetric radiosurgery treatment planning tool
s, feasible treatment plans were developed for each target. The treatment p
lans generated for the phantom targets showed excellent dose conformity and
acceptable dose homogeneity within the target volume. The algorithm was ab
le to generate a radiosurgery plan conforming to the Radiation Therapy Onco
logy Group (RTOG) guidelines on radiosurgery for every clinical and phantom
target examined.
Conclusions: This automated planning method can serve as a valuable tool to
assist treatment planners in rapidly and consistently designing conformal
multiple isocenter radiosurgery treatment plans. (C) 2000 Elsevier Science
Inc.