S. Colagrande et al., Value of hepatic arterial phase CT versus lipiodol ultrafluid CT in the detection of hepatocellular carcinoma, J COMPUT AS, 24(6), 2000, pp. 878-883
Citations number
21
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Objective: To evaluate the role of hepatic arterial phase (HAP) spiral comp
uted tomography (CT), as compared with iodized oil (Lipiodol ultrafluid [LU
F]) CT for revealing nodular hepatocellular carcinomas (HCC).
Methods: Twenty-four cirrhotic patients underwent two-phase HCT examination
: HAP 25 seconds and portal phase 70 seconds after injection of 1.5 mL/Kg c
ontrast medium. All patients also underwent hepatic angiography and intraar
terial infusion of iodized oil; LUF CT was performed 3-4 weeks after infusi
on. HCT images were compared with LUF CT images for detection of hepatic no
dules.
Results: We found no significant difference between the sensitivity of HAP
CT and LUF CT for nodules >10 mm, while HAP CT was more sensitive than LUF
CT in revealing nodules <10 mm (47 vs. 27, p < 0.001).
Conclusions: HCT should be considered as the first method for the detection
of HCC, whereas LUF CT should be used only for therapy.