Quantum mechanics is already 100 years old, but remains alive and full of c
hallenging open problems. On one hand, the problems encountered at the fron
tiers of modern theoretical physics like quantum gravity, string theories,
etc. concern quantum theory, and are at the same time related to open probl
ems of modern mathematics. But even within non-relativistic quantum mechani
cs itself there are fundamental unresolved problems that can be formulated
in elementary terms. These problems are also related to challenging open qu
estions of modern mathematics; linear algebra and functional analysis in pa
rticular. Two of these problems will be discussed in this article: (a) the
separability problem, i.e. the question when the state of a composite quant
um system does not contain any quantum correlations or entanglement; and (b
) the distillability problem, i.e. the question when the state of a composi
te quantum system can be transformed to an entangled pure state using local
operations (local refers here to component subsystems of a given system).
Although many results concerning the above mentioned problems have been obt
ained (in particular in the last few years in the framework of quantum info
rmation theory), both problems remain until now essentially open. We will p
resent a primer on the current state of knowledge concerning these problems
, and discuss the relation of these problems to one of the most challenging
questions of linear algebra: the classification and characterization of po
sitive operator maps.