Steroidal glycosides from the aerial parts of Polianthes tuberosa

Authors
Mimaki, Y Yokosuka, A Sashida, Y
Citation
Y. Mimaki et al., Steroidal glycosides from the aerial parts of Polianthes tuberosa, J NAT PROD, 63(11), 2000, pp. 1519-1523
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
11
Year of publication
2000
Pages
1519 - 1523
Database
ISI
SICI code
0163-3864(200011)63:11<1519:SGFTAP>2.0.ZU;2-P
Abstract
A chemical investigation of the aerial parts of Polianthes tuberosa resulte d in the isolation of a new bisdesmosidic cholestane glycoside (1) and thre e new spirostanol saponins (2-4), along with a known cholestane glycoside. The structures of new glycosides were determined by spectroscopic analysis; including 2D NMR spectroscopic data, and the results of hydrolytic cleavag e. The isolated compounds were evaluated for their cytotoxic activity on HL -60 human promyelocytic leukemia cells.