Two new 26,27-cyclosterols from the marine sponge Stringylophora corticata

Authors
Umeyama, A Ito, S Yoshigaki, A Arihara, S
Citation
A. Umeyama et al., Two new 26,27-cyclosterols from the marine sponge Stringylophora corticata, J NAT PROD, 63(11), 2000, pp. 1540-1542
Citations number
6
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
11
Year of publication
2000
Pages
1540 - 1542
Database
ISI
SICI code
0163-3864(200011)63:11<1540:TN2FTM>2.0.ZU;2-B
Abstract
Two novel steroids with a cyclopropane ring at C-25 and C-26, 7-oxopetroste rol (1) and 7 alpha -hydroxypetrosterol (2), along with two known compounds , petrosterol (3) and 23,24-dihydrocalysterol (4), have been isolated from the Japanese marine sponge Strongylophora corticata. The structures of 1 an d 2 were determined as 26,27-cyclo-24,27-dimethyl-3 beta -hydroxycholest-5- en-7-one and 26,27-cyclo-24,27-dimethylcholest-5-en-3 beta ,7 alpha -diol o n the basis of spectroscopic investigations.