Echinophyllins C-F, new nitrogen containing clerodane diterpenoids from Echinodorus macrophyllus

Authors
Kobayashi, J Sekiguchi, M Shimamoto, S Shigemori, H Ohsaki, A
Citation
J. Kobayashi et al., Echinophyllins C-F, new nitrogen containing clerodane diterpenoids from Echinodorus macrophyllus, J NAT PROD, 63(11), 2000, pp. 1576-1579
Citations number
6
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
11
Year of publication
2000
Pages
1576 - 1579
Database
ISI
SICI code
0163-3864(200011)63:11<1576:ECNNCC>2.0.ZU;2-9
Abstract
Four new nitrogen-containing clerodane diterpenoids, echinophyllins C-F (1- 4), were isolated from the leaves of the Brazilian medicinal plant Echinodo rus macrophyllus ("Chapeu-de-couro"), and their structures and relative ste reochemistry were elucidated from their spectroscopic data. Compounds 1-4 p ossess an alpha,beta -unsaturated gamma -lactam ring consisting of a clerod ane diterpene unit and an amine moiety.