IMPROVED DIFLUORINATION OF CYCLOHEXENONES USING MORPH-DAST BY THE APPLICATION OF ULTRA-HIGH PRESSURE

2,6- and 6,6- difluorinated alpha-substituted cyclohexenes have been p repared by the action of morpholinosulfur trifluoride on the correspon ding cyclohex-2-enones under thermal conditions. The overall efficienc y of this process has been significantly improved by the application o f ultra high pressure (10-19Kbar). Investigations into the scope of th is methodology have resulted in the preparation of the novel fluorinat ed compounds: 6,6-difluorolimonene and 3,3-difluoro-4-cholestene.