TOTAL SYNTHESIS OF (-)-BALANOL

Authors
MIYABE H TORIEDA M KIGUCHI T NAITO T
Citation
H. Miyabe et al., TOTAL SYNTHESIS OF (-)-BALANOL, Synlett, (5), 1997, pp. 580
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):5<580:TSO(>2.0.ZU;2-Q
Abstract
The total synthesis of (-)-balanol, a potent protein kinase C inhibito r, is described. The synthesis includes a radical cyclization approach to the hexahydroazepine-containing fragment and a biomimetic route to the benzophenone fragment.