Recent advances in the use of drugs for the treatment of two major sexual d
ysfunctions in men, erectile dysfunction and premature ejaculation, are pre
sented. Optimal parameters for use, overall efficacy, and actual or presume
d mechanism of action are discussed for both oral and nonoral medications t
hat have been commonly used in the past 10 to 15 years. The limitations of
the specific pharmacotherapies for treating sexual dysfunction, as well as
the limitations of current research investigating various pharmacological o
ptions, are acknowledged. General issues surrounding the rising use of drug
s for treating sexual dysfunction are also discussed, including the value o
f considering therapeutic seals and treatment options that focus on more th
an just restoration of genital function.