H-1 and C-13 NMR spectral characterization of some antimalarial in vitro -3-amino-9-methyl-1H-pyrazolo[3,4-b]-4-quinolones

Authors
Charris, JE Dominguez, JN Lobo, G Cordero, MI Lopez, SE Mendez, B Pekerar, S Riggione, F
Citation
Je. Charris et al., H-1 and C-13 NMR spectral characterization of some antimalarial in vitro -3-amino-9-methyl-1H-pyrazolo[3,4-b]-4-quinolones, MAGN RES CH, 38(12), 2000, pp. 1039-1040
Citations number
9
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MAGNETIC RESONANCE IN CHEMISTRY
ISSN journal
07491581 → ACNP
Volume
38
Issue
12
Year of publication
2000
Pages
1039 - 1040
Database
ISI
SICI code
0749-1581(200012)38:12<1039:HACNSC>2.0.ZU;2-S
Abstract
We report the H-1 NMR and C-13 NMR chemical shifts and J(H,H), J(H,F) and J (C,F) coupling constants of nine 3-amino-9-methyl- 1H-pyrazolo[3,4-b]-4-qui nolone derivatives, all of them active against Plasmodium falciparum in vit ro. They were characterized and assigned on the basis of H-1,C-13 and C-13- H-1 (short- and long-range) correlated spectra. Copyright (C) 2000 John Wil ey & Sons, Ltd.