An IBM PC-based real-time data acquisition, monitoring and analysis system
for experimental haemodynamic studies was developed. Comprehensive haemodyn
amic signals, such as aortic and left ventricular pressures, aortic and cor
onary blood flows, two segmental lengths, two segmental thicknesses, electr
ocardiogram and airway pressure, were acquired and monitored to assess card
iac function. The system performs computer-aided analysis and derivations o
n a number of haemodynamic parameters and cardiac function indices. The sys
tem has been tested and validated extensively over a number of series of ex
perimental haemodynamic studies to investigate the effects of anaesthetic a
gents, cardiovascular drugs, and changes in loading on normal and criticall
y ischaemic myocardium of anaesthetised laboratory subjects. Without this s
pecialised and automated system, the analysis of the data acquired from the
haemodynamic studies would be too time-consuming and could not be fully pe
rformed. (C) 2000 IPEM. Published by Elsevier Science Ltd. All rights reser
ved.