Rp. Clarke, Does longer-term memory storage never become overloaded, and would such overload cause Alzheimer's disease and other dementia?, MED HYPOTH, 55(5), 2000, pp. 419-428
Citations number
56
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
According to an uncritically accepted axiom, the human brain's capacity for
longer-term memory storage is never overloaded. This viewpoint is shown to
be contrary to all evidence and beyond reasonable credibility. The entire
currently obtainable evidence for or against overload comes via the presenc
e or absence of its manifestation in behaviour. This manifestation would be
as an incurable, deteriorating, specific form of memory disorder, associat
ed with old age and consequent to increased data-inputting and reductions o
f brain capacity. There is in fact such a disorder, namely Alzheimer's dise
ase and other dementia. This relationship provides elegant explanations for
various peculiar findings, without encountering any counter-evidence. The
premorbid accumulation of tangles in the hippocampus is explained via an in
tegration of existing hippocampus theories. Long-term low doses of drugs th
at reduce memory formation could prevent or delay dementia. TV-watching, vi
deos, and some memory-enhancing nootropic drugs could increase risk. (C) 20
00 Harcourt Publishers Ltd.