Asymmetric allylic substitution reactions with a xylophos-pd catalyst

Authors
Pamies, O Ruiz, A Net, G Claver, C Kalchhauser, H Widhalm, M
Citation
O. Pamies et al., Asymmetric allylic substitution reactions with a xylophos-pd catalyst, MONATS CHEM, 131(11), 2000, pp. 1173-1179
Citations number
31
Categorie Soggetti
Chemistry
Journal title
MONATSHEFTE FUR CHEMIE
ISSN journal
00269247 → ACNP
Volume
131
Issue
11
Year of publication
2000
Pages
1173 - 1179
Database
ISI
SICI code
0026-9247(200011)131:11<1173:AASRWA>2.0.ZU;2-8
Abstract
The chiral diphosphine ligand xylophos (1) was tested as an auxiliary in pa lladium catalyzed allylic substitution reactions. Whereas its activity was found to be generally good only in the case of 1,3-diphenylprop-2-en-1-yl a cetate, a fair level of asymmetric induction was achieved with sodium dimet hyl malonate (83% ee) and benzylamine (66% ee) as nucleophiles.