Fornix based trabeculectomy with Wise's suture technique in Chinese patients

Objective: To assess the safety and efficacy of fornix-based trabeculectomy with Wise's suture technique in Chinese subjects. Design: A retrospective noncomparative case series. Participants: Forty-eight eyes of 44 Chinese subjects that underwent fornix -based trabeculectomy combined with intraoperative 0.4 mg/ml mitomycin-C fo r 3 to 5 minutes were studied. Intervention: Conjunctival wound closure of all eyes was with the Wise's te chnique using 9-0 nylon suture to prevent leakage at the corneolimbal inter face. Main Outcome Measures The success rate, with or without antiglaucoma medica tion, the complication rate, and the longevity of the drainage blebs were a nalyzed. Results: At a mean follow-up period of 21.8 +/- 4.5 months, 75% (36 eyes) h ad postoperative intraocular pressure of 21 mmHg or less. Of these, 23 eyes (47.9%) required no antiglaucoma medication, 7 eyes (14.6%) required one m edication, 3 eyes (6.3%) required two medications, and 3 eyes (6.3%) requir ed three medications. Ten eyes (21%) had early wound leak. Two eyes (4.2%) required surgical repair. Two eyes (4%) had hypotonous maculopathy. No othe r major complications were encountered. Conclusions Fornix-based trabeculectomy with adjunctive mitomycin-G using W ise's suture technique appears to be both safe and effective in Chinese sub jects. (C) 2000 by the American Academy of Ophthalmology.