Homogeneous RuCl2(PPh3)(3)-catalyzed regioselective liquid-phase transfer hydrogenation of carbon-carbon double bond in chlorobenzylidene ketones with ethylene glycol as hydrogen donor

Authors
Mukhopadhyay, S Yaghmur, A Benichou, A Sasson, Y
Citation
S. Mukhopadhyay et al., Homogeneous RuCl2(PPh3)(3)-catalyzed regioselective liquid-phase transfer hydrogenation of carbon-carbon double bond in chlorobenzylidene ketones with ethylene glycol as hydrogen donor, ORG PROC R, 4(6), 2000, pp. 571-574
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC PROCESS RESEARCH & DEVELOPMENT
ISSN journal
10836160 → ACNP
Volume
4
Issue
6
Year of publication
2000
Pages
571 - 574
Database
ISI
SICI code
1083-6160(200011/12)4:6<571:HRRLTH>2.0.ZU;2-U
Abstract
The regioselective transfer hydrogenation of a carbon-carbon double bond of different chlorobenzylidene ketones is effectuated in ethylene glycol with a very high selectivity in the presence of homogeneous, tris(triphenylphos phine)ruthenium-(II) chloride catalyst. Different important process paramet ers such as temperature, catalyst loading, and reaction period are studied. The reaction follows a first order kinetics, and the energy of activation was found to be 52 kJ/mol.