Thymic carcinoma, systemic lupus erythematosus, and hypertrophic pulmonaryosteoarthropathy in an 11-year-old boy: A novel association

Citation
A. Di Cataldo et al., Thymic carcinoma, systemic lupus erythematosus, and hypertrophic pulmonaryosteoarthropathy in an 11-year-old boy: A novel association, PED HEM ONC, 17(8), 2000, pp. 701-706
Citations number
14
Categorie Soggetti
Pediatrics
Journal title
PEDIATRIC HEMATOLOGY AND ONCOLOGY
ISSN journal
08880018 → ACNP
Volume
17
Issue
8
Year of publication
2000
Pages
701 - 706
Database
ISI
SICI code
0888-0018(200012)17:8<701:TCSLEA>2.0.ZU;2-M
Abstract
thymic carcinoma is exceptionally rare in children and it has never previou sly been associated with autoimmune disorders. The authors report the case of an 11-year-old boy with thymic carcinoma, hypertrophic pulmonary osteoar thropathy, and an autoimmune disease that resembled systemic lupus erythema tosus. To their knowledge, this is the first case of such complex clinical findings. the tumor was of high grade histologically and the boy died after 1 year, in spite of chemotherapy and radiotherapy. A review is presented o f the available medical literature on thymic malignancy in childhood.