A. Di Cataldo et al., Thymic carcinoma, systemic lupus erythematosus, and hypertrophic pulmonaryosteoarthropathy in an 11-year-old boy: A novel association, PED HEM ONC, 17(8), 2000, pp. 701-706
thymic carcinoma is exceptionally rare in children and it has never previou
sly been associated with autoimmune disorders. The authors report the case
of an 11-year-old boy with thymic carcinoma, hypertrophic pulmonary osteoar
thropathy, and an autoimmune disease that resembled systemic lupus erythema
tosus. To their knowledge, this is the first case of such complex clinical
findings. the tumor was of high grade histologically and the boy died after
1 year, in spite of chemotherapy and radiotherapy. A review is presented o
f the available medical literature on thymic malignancy in childhood.