Synthesis of 3-(2-mercapto-4-thiazolyl)-2H-1-benzopyran-2-one and its derivatives

Authors
Rao, VR Adityavardhan, V Srimanth, K
Citation
Vr. Rao et al., Synthesis of 3-(2-mercapto-4-thiazolyl)-2H-1-benzopyran-2-one and its derivatives, PHOSPHOR SU, 164, 2000, pp. 293-298
Citations number
23
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
ISSN journal
10426507 → ACNP
Volume
164
Year of publication
2000
Pages
293 - 298
Database
ISI
SICI code
1042-6507(2000)164:<293:SO3AID>2.0.ZU;2-#
Abstract
Treatment of 3-(2-bromoacetyl)coumarins with ammonium dithiocarbamate provi des 3-(2-mercapto-4-thiazolyl)-2H-1-benzopyran-2-one (II) but not 4-hydroxy -4-(3-coumarinyl)thiazolidine-2-thione (I). II undergoes smooth condensatio n with alkyl, aralkyl, phenacyl and acid halides to give corresponding thio ethers and thioesters (III) respectively. The structures of the newly synth esized compounds were established on the basis of spectral data (IR PMR and MS).