A FACILE SYNTHESIS OF NEW [1,2,4]TRIAZOLO[3,4-D][1,3,5]DITHIAZINES INVOLVING ACIDLABILE METHANESULPHINYL LEAVING GROUP

Authors
YADAV LDS VAISH A SHARMA S
Citation
Lds. Yadav et al., A FACILE SYNTHESIS OF NEW [1,2,4]TRIAZOLO[3,4-D][1,3,5]DITHIAZINES INVOLVING ACIDLABILE METHANESULPHINYL LEAVING GROUP, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(5), 1997, pp. 442-444
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
36
Issue
5
Year of publication
1997
Pages
442 - 444
Database
ISI
SICI code
0376-4699(1997)36:5<442:AFSON[>2.0.ZU;2-#
Abstract
Nucleophilic addition of the amine function of 5-aryl-3-methanesulphin ylmethylthio-1, 2, 4-triazoles 2a, b to carbon disulphide and aryl/cyc lohexyl isothiocyanates furnishes adducts 4a-h which undergo a facile intramolecular cyclisation via a nucleophilic displacement to yield th e corresponding [1, 2, 4]triazolo[3,4-d][1,3,5]dithiazines 5a-h with t he loss of the acid-labile methanesulphinyl leaving group as methanesu lphenic acid.