Sixteen patients with tardive dyskinesia were treated with vitamin E i
n an open trial of on-off-on design. Abnormal involuntary movement sca
le (AIMS) ratings were performed in every phase of the study. The pati
ents exhibited a significant reduction in their mean AIMS score during
vitamin E treatment. Thus, this finding may suggest a possible role f
or vitamin E in the treatment of tardive dyskinesia. (C) 1997 by John
Wiley & Sons, Ltd.