THE COINCIDENCE OF SCHIZOPHRENIA AND IDIOPATHIC PARKINSONS-DISEASE - SUCCESSFUL TREATMENT WITH A COMBINATION OF ANTIPARKINSONIAN DRUGS AND ATYPICAL ANTIPSYCHOTIC-DRUGS

Authors
WATANABE M KODAMA Y SHIMIZU K ICHINOWATARI N
Citation
M. Watanabe et al., THE COINCIDENCE OF SCHIZOPHRENIA AND IDIOPATHIC PARKINSONS-DISEASE - SUCCESSFUL TREATMENT WITH A COMBINATION OF ANTIPARKINSONIAN DRUGS AND ATYPICAL ANTIPSYCHOTIC-DRUGS, Human psychopharmacology, 12(3), 1997, pp. 271-275
Citations number
23
Categorie Soggetti
Psychology,"Pharmacology & Pharmacy","Clinical Neurology
Journal title
Human psychopharmacology → ACNP
ISSN journal
08856222
Volume
12
Issue
3
Year of publication
1997
Pages
271 - 275
Database
ISI
SICI code
0885-6222(1997)12:3<271:TCOSAI>2.0.ZU;2-X
Abstract
It is rare for schizophrenia and idiopathic Parkinson's disease to occ ur in the same patient. This report describes a case in which a chroni c schizophrenic patient later developed idiopathic Parkinson's disease . Both the psychotic and the parkinsonian symptoms of the patient were well controlled with the combination of antiparkinson drugs (bromocri ptine and L-threo-DOPS) and atypical antipsychotic drugs (sulpiride an d thioridazine). It is suggested that excessive dopaminergic activity in the mesolimbic system may coexist with dopaminergic deficiency in t he nigrostriatal system in this patient. (C) 1997 by John Wiley & Sons , Ltd.