ARE IMMUNOLOGICAL MARKERS, SOCIAL AND PERSONAL RESOURCES, OR A COMPLAINT-FREE STATE PREDICTORS OF PROGRESSION AMONG HIV-INFECTED PATIENTS

Predictors of disease progression were studied in 89 asymptomatic HIV- infected patients who were prospectively evaluated for psychosocial va riables and the development of clinical symptoms over a period of 2 ye ars. The subjects were assessed for symptoms laboratory measures demog raphic variables, social and personal resources mental status alcohol, nicotine and drug use, sexual activity and risk behaviour, and sexual ly transmitted diseases After 1 year, 17% of the patients had develope d HIV-associated symptoms (symptomatic disease or AIDS), and after 2 y ears, 32% had developed symptoms or had died. In the multivariate anal yses the baseline CD4 count was the only significant predictor of dise ase progression during both observation periods. Psychosocial measures did not predict the progression of HIV infection.