Treatment of multiple myeloma

The chief advances observed over the last 15 years in the treatment of mult iple myeloma arise from intensive procedures and in particular autologous b one marrow transplantation. However, even if autologous bone marrow transpl antation increases the rate of total remissions, no plateau is yet observab le in the survival curve and transplantation is probably not a curative the rapy. Hopes for the future seem to rest on intensive chemotherapy combined with innovative therapeutic approaches such as diphosphonates, thalidomide or immunotherapy.