L. Cantarelli et al., A case of pseudophlebitis of the v. saphena magna: focal nodular myositis of m. gracilis, SCHW MED WO, 130(44), 2000, pp. 1692-1694
A case of focal myositis in a healthy 68-year-old woman is described. The p
atient was admitted for evaluation of a painful soft-tissue mass localised
on the medial side of the left thigh, initially misdiagnosed as thrombophle
bitis of the v. saphena magna. Laboratory data were normal, in particular s
edimentation rate and muscle enzyme levels. After exclusion of venous throm
bosis, the mass localised in the left m. gracilis was surgically removed. H
istologic examination of the biopsy specimen showed muscle cell necrosis an
d severe inflammation, with lymphocytic infiltration leading to the diagnos
is of focal myositis. This is a rare benign inflammatory pseudotumour of sk
eletal muscle. The aetiology and pathogenesis of the disease remain unclear
. It is most commonly seen in the lower extremities and may mimic thromboph
lebitis or soft-tissue neoplasm. Ultrasound and magnetic-resonance scans ar
e helpful, but definitive diagnosis is obtained only by histology. Because
recurrent lesions in other skeletal muscles are possible, and a third of pa
tients develop polymyositis, a follow-up of several years is recommended.