Optimal selection of sampling strategies is considered for the prediction o
f spatio-temporal processes in a state-space-model framework. General condi
tions are assumed in relation to the basic elements of the problem: modelli
ng space-time interaction, formulating prediction objectives, defining the
type and structure of sampling configurations, and formulating optimality c
riteria. An empirical study, involving a diversity of cases selected within
two different examples, is carried out with the aim of illustrating some a
spects of interest inherent to the problem considered, with special emphasi
s on highlighting the important effect of the space-time interaction struct
ure on the ratios of information associated with different possible samplin
g configurations.