We report on a patient with essential thrombocythemia treated with hydroxyu
rea who became febrile 3 weeks after the treatment was started. After drug
withdrawal, the fever resolved but after rechallenge there was recurrence o
f the fever. Although hydroxyurea-induced fever is rare, this drug must be
added to the list of drugs that produce fever and the physicians should be
aware of this possibility. Copyright (C) 2000 S. Karger AG. Basel.