Vestibular neuropathy accompanying auditory and peripheral neuropathies

Objective: To define the incidence of measurable vestibular disorders in pa tients with auditory and peripheral neuropathies. Design: Descriptive study of the case features of auditory neuropathy in 14 patients, 8 of whom had concomitant peripheral neuropathies. Setting: University referral center. Patients: Fourteen patients aged from 10 to 75 years and diagnosed as havin g auditory neuropathy, 8 of whom had concomitant peripheral neuropathies. Main Outcome Measures: Incidence of abnormal vestibular caloric test result s and the relationship of such incidence to clinical variables including th e ages of the subjects, the presence of a concomitant peripheral neuropathy , vestibular symptoms, and audiological findings. Results: Abnormal vestibular caloric test results occurred in 9 of the 14 p atients. These 9 patients were on average older (35.6 years) than patients with normal caloric responses (17.8 years). Seven of the 9 patients with ab normal caloric responses had concomitant peripheral neuropathies compared w ith only I of the 5 patients with normal caloric responses. None of the 14 patients experienced symptoms of vestibular disorder. Conclusions: Asymptomatic vestibular disorders are common in patients with auditory neuropathy when a peripheral neuropathy is also present. The reaso n for the abnormal vestibular test results is likely a neuropathy of the ve stibular nerves.