2,4,5-trisubstituted imidazoles: Novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 2

Authors
Zhang, CZ Sarshar, S Moran, EJ Krane, S Rodarte, JC Benbatoul, KD Dixon, R Mjalli, AMM
Citation
Cz. Zhang et al., 2,4,5-trisubstituted imidazoles: Novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 2, BIOORG MED, 10(23), 2000, pp. 2603-2605
Citations number
12
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
23
Year of publication
2000
Pages
2603 - 2605
Database
ISI
SICI code
0960-894X(200012)10:23<2603:2INNMO>2.0.ZU;2-5
Abstract
Solution-phase combinatorial chemistry was applied to the optimization and development of clinical candidate OC144-093 (22), a novel and nontoxic modu lator of P-glycoprotein mediated multidrug resistance. (C) 2000 Elsevier Sc ience Ltd. All rights reserved.