A suitable procedure to choose antimicrobials as controlling agents in fermentations performed by bacteria

This work evaluated the influence of nitrofurantoin, erythromycin and strep tomycin at 50, 25 and 12,5% of the minimal inhibitory concentration (MIC) o n maximum specific growth rate (mu (max)) and specific polymer accumulation rate (mu (PHB)) Of Alcaligenes eutrophus, considered resistant to those an timicrobials. Nitrofurantoin strongly affected mu (max) even at 50% MIC. St reptomycin moderately affected mu (max) Only at 50%MIC. Nitrofurantoin show ed the most harmful effect on mu (PHB) when 50% MIC was applied and erythro mycin was not harmful.