Treatment of many childhood malignancies involves surgery, radiotherapy and
chemotherapy. If the child survives, normal physical development can be im
paired and abnormalities with, anaesthetic implications may be present. We
discuss two women with a range of problems who presented for obstetric anae
sthesia, having survived childhood malignancies. Common features included a
nthracycline cardiotoxicity and short stature. Both patients received incre
mental spinal anaesthesia in order to titrate the dose of local anaesthetic
required to produce an adequate block height and to minimize cardiovascula
r instability.