Chemical constituents of MeOH extracts of cigarette smoke were studied. Two
new alkaloids, named cigatin A (1), 2-(Pyridine-3-yloxy)-benzene-1',4'-dio
l and B (2), 2-(4-Methyl-pyridin-3-yloxy)-benzene-1',4'-diol were isolated
from a mainstream condensate of cigarette together with seven known alkaloi
ds. Their structures were determined on the basis of spectral data and chem
ical methods.