Trifluoromethanesulfonic anhydride-promoted alpha-bromination of ketones with Grignard reagent or magnesium bromide

Authors
Nishiyama, T Ono, Y Kurokawa, S Kimura, S
Citation
T. Nishiyama et al., Trifluoromethanesulfonic anhydride-promoted alpha-bromination of ketones with Grignard reagent or magnesium bromide, CHEM PHARM, 48(12), 2000, pp. 1999-2002
Citations number
25
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
48
Issue
12
Year of publication
2000
Pages
1999 - 2002
Database
ISI
SICI code
0009-2363(200012)48:12<1999:TAAOKW>2.0.ZU;2-Z
Abstract
The direct alpha -bromination of various ketones using trifluoromethanesulf onic anhydride and Grignard reagent or magnesium bromide in ether gave the corresponding alpha -bromo ketones in moderate to good yields under mild re action conditions.