Sw. Lim et Cl. Goh, Epidemiology of eczematous cheilitis at a tertiary dermatological referralcentre in Singapore, CONTACT DER, 43(6), 2000, pp. 322-326
In a retrospective epidemiologic study of 202 patients with eczematous chei
litis attending a patch test clinic, females (182 (90%)) predominated over
males (20 (10%)). The mean age of our patients was 30.9 years. There was no
significant difference between the mean age of females (31 years) presenti
ng with cheilitis compared to males (29 years). Endogenous cheilitis (53%)
was the commonest diagnosis, followed by allergic contact dermatitis (34%)
and irritant contact dermatitis (5.4%). A personal history of atopy was rec
orded in 33%. There was no significant difference in the prevalence of atop
y between the sexes or among the diagnoses. The mean duration of cheilitis
was 16.4 months. The duration was significantly longer in males (29 months)
than in females (15 months) (p=0.004). The mean number of positive patch t
est reaction in patients with allergic contact cheilitis (2.8) was signific
antly higher than in those with irritant contact cheilitis (0.2) (p= 0.012)
or endogenous cheilitis (0.5) (p=0.00). The commonest cause of allergic co
ntact cheilitis were lip cosmetics, including lipsticks and lipbalms, follo
wed by toothpastes. The commonest cause of irritant contact cheilitis was l
ip-licking, lipsticks and medication. In 81/202 (40%) patients, 1 or more c
auses of contact cheilitis could be ascertained. In females, lip cosmetics
were the commonest cause, accounting for 54% (44/81) of cases. Toothpastes
accounted for 21% (17/81), followed by topical medication 7% (6/81). For ma
les, toothpastes were the commonest cause of allergic contact cheilitis. Ri
cinoleic acid and the patient's own lip preparations were the commonest rel
evant contact allergens.