Crystal structure of t-boc-O-benzyl-L-tyrosyl-D-alanyl-L-(O-benzyl)-glutamate : monohydrate

The crystal structure of a tripeptide, t-boc-O-benzyl-L-tyrosyl-D-alanyl-L- (O-benzyl)-glutamate has been determined by direct methods, and refined by full-matrix least squares procedures to a final R-index of 0.060. The pepti de conformation corresponds to a reverse turn - Type II, stabilized by a 4 --> 1 N-H . . .O hydrogen bond, with the amide proton also forming a bifurc ated hydrogen bond to an oxygen atom from the C-terminus of a neighbouring molecule.