Purpose: The anatomy of the mandible was examined by measuring the cro
ss-sectional area (CSA) of multiple regions of 10 fully dentulous hemi
mandibles to provide a better understanding of regional structural dif
ferences that may have implications regarding biomechanical strength,
surgical reconstruction, and fracture site frequency. Materials and Me
thods: Fifteen cuts from the condyle to the symphysis were made of eac
h hemimandible (n = 150 cuts). A Zeiss Videoplan digitizer was used to
determine the CSA. Results: The total CSA through the condyle was gre
ater than the CSA through the condylar neck, The GSA through the ramus
exceeded that of the condylar neck, The total CSA of the midramus was
significantly greater than that of the upper ramus. The total CSA at
the body, parasymphysis, and symphysis was significantly greater than
at the mid-angle. The total CSA of the cortex increased anteriorly; th
ese differences become significant between the condylar neck and the b
ody, parasymphysis, and symphysis, The total CSA, and the CSA of the c
ortex and spongiosa, remained relatively constant from the inferior an
gle anteriorly. Conclusions: Significant differences exist in the CSA
at different points, with an increase in the total, cortical, and spon
giosal CSA anteriorly from the condylar neck to the angle. The total C
SA and the CSA of the cortex and spongiosa remain relatively constant
anterior to the inferior angle, These data suggest that bony CSA alone
is not the sole factor in determining fracture site frequency.