Electroencephalogram and repetitive transcranial magnetic stimulation

Scalp recordings of the electroencephalogram (EEG) have been used in associ ation with repetitive transcranial magnetic stimulation (rTMS) investigatio ns as a safety measure in monitoring ongoing EEG activity and as a neurophy siologic tool in examining the specific effects induced by the magnetic sti mulus On the EEG or evoked potentials (EPs). Medline review on the use of E EG or EPs with rTMS reveals that this area has been largely unexplored. Lim ited available studies ies attest to the potentinal for studies combining E EG/EPs and rTMS to be useful in further elucidating the normal brain physio logy. Herein, we report on our experience with continuous EEG sampling comb ined with rTMS in patients with major depression (n = 14), schizophrenia (n = 7), and obsessive-compulsive disorder (n = 5). Our data support the prac tice of using continuous EEG monitoring when the stimulation parameters fal l outside established safety guidelines. (C) 2000 Wiley-Liss, Inc.