Lichen scrofulosorum is a rare entity of children and young adults. The cut
aneous lesions are typically symptomless papular eruptions, associated with
a strong Mantoux reaction, tuberculosis of lymph nodes and/or other organs
. Eight patients between the ages of 5 and 36 years were included in this s
eries. Lesions were commonly seen on the trunk, though a case of involvemen
t of the palms and soles was also observed. Pulmonary tuberculosis was seen
in 5 adults; 1 patient each had pleural effusion, tuberculous adenitis and
tuberculoma, respectively. Histopathological examination typically showed
epithelioid cell granulomas around hair follicles. The histogenesis is uncl
ear, a type IV hypersensitivity reaction provoked by chronic tubercular inf
ection is probable. The patients responded well to antituberculous therapy.
Copyright (C) 2000 S. Karger AG. Basel.