Voltammetric trace analysis of DNA and RNA

Citation
S. Reher et al., Voltammetric trace analysis of DNA and RNA, FRESEN J AN, 368(7), 2000, pp. 720-726
Citations number
27
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
ISSN journal
09370633 → ACNP
Volume
368
Issue
7
Year of publication
2000
Pages
720 - 726
Database
ISI
SICI code
0937-0633(200012)368:7<720:VTAODA>2.0.ZU;2-5
Abstract
A voltammetric determination of DNA/RNA is described. The new aspect is the use of the extracellular endonuclease Serratia marcescens in the sample pr eparation. Using this enzyme it is possible to determine DNA/RNA with a det ection limit of 2-5 pg/mL. This satisfies the requirements of the WHO and t he FDA.