Massive bleeding from a gastric erosion after transcatheter arterial chemoembolization for hepatocellular carcinoma in a patient with mild haemophilia A

We observed massive bleeding from a gastric erosion following transcatheter arterial chemoembolization (TAE) in a patient with mild haemophilia A. A 7 8-year-old haemophiliac (factor VIII level over 60%) received TAE with farm orubicin and spongel. Haematemesis and melena with loss of consciousness oc curred 9 days after TAE, and endoscopy revealed superficial erosions with o ozing. Toxic effects of the anticancer drug in conjunction with the bleedin g disorder may have caused the massive bleeding. We should always consider the possibility of unexpected complications in patients with bleeding disor ders; gastrointestinal bleeding can develop during treatment for liver tumo urs.