Ma. Massa et al., Syntheses of new racemic N-G-(1-lminoethyl)phosphalysine derivatives as potential inhibitors of nitric oxide synthase, HETEROAT CH, 11(7), 2000, pp. 505-511
The efficient syntheses of three Mew racemic N-G-(1-iminoethyl)phosphalysin
e derivatives are reported where the lysine carboxylate group is systematic
ally replaced by phosphonic acid, 4, methyl phosphinic acid, 5, and phosphi
nic acid, 6. These compounds were evaluated as potential inhibitors of the
three isoforms of human nitric oxide synthase. (C) 2000 John Wiley & Sons,
Inc.