A practical and effective asymmetric synthesis of 2-amino-3,3,3-trifluoropropanephosphonic acid

Authors
Citation
Jb. Xiao et Cy. Yuan, A practical and effective asymmetric synthesis of 2-amino-3,3,3-trifluoropropanephosphonic acid, HETEROAT CH, 11(7), 2000, pp. 541-545
Citations number
16
Categorie Soggetti
Chemistry
Journal title
HETEROATOM CHEMISTRY
ISSN journal
10427163 → ACNP
Volume
11
Issue
7
Year of publication
2000
Pages
541 - 545
Database
ISI
SICI code
1042-7163(2000)11:7<541:APAEAS>2.0.ZU;2-8
Abstract
A practical and effective synthesis of 2-amino-3, 3, 3-trifluoropropanephos phonic acid of high stereochemical purity was successfully achieved by a ba se-induced [1,3]-proton shift reaction of the intermediate 2-imino-3,3,3-tr ifluoropropanephosphate. (C) 2000 John Wiley & Sons, Inc.