Physiochemical measurements in liquids by simple HPLC instrumentation

A method is described for measuring physicochemical quantities in liquid an d liquid/solid systems by means of HPLC instrumentation. It has been applie d with benzene as analyte, chloroform or acetonitrile as liquid solvents, a nd silica gel as solid phase stuck on the internal wall of a cylindrical tu be. The relevant theoretical analysis has been found for determining diffusion coefficients into liquid systems, and kinetic parameters pertaining to the adsorption, desorption, and surface reaction of the analyte with the solid stuck on the wall. The method has been tested for various lengths of time k eeping the system stagnant before analysing it by HPLC.