Ji. Jimenez et al., 'Upenamide: An unprecedented macrocyclic alkaloid from the Indonesian sponge Echinochalina sp., J ORG CHEM, 65(25), 2000, pp. 8465-8469
'Upenamide (1) represents a new class of macrocyclic marine alkaloid posses
sing both spiro-oxaquinolizidinone and hemiaminal ring systems. It was isol
ated from the Indonesian sponge Echinochalina sp. The gross structure of I
was:elucidated by spectroscopic methods and accurate mass measurements. A s
uggestion is made as to its biogenetic origin.