A decline in muscle mass and function, and in the mass and integrity of the
skeletal system, are well-known consequences of aging. These changes impin
ge on the functional performance required for independent living and contri
bute to frailty and fracture risk. Resistance exercise has been shown to be
an effective mode to circumvent age-related changes in the muscular system
, although the benefit of exercise on bone mass in the aging skeleton is co
mparatively modest at best. This brief review highlights results from sever
al studies that we have undertaken in older adults, examining aspects of th
e resistance training prescription as well as the potential beneficial role
of hormones. What is common to all of these studies is the high degree of
residual plasticity that remains in aging skeletal muscle. Risk factors for
falls and fracture include reduced bone mass, muscle weakness, impaired ba
lance, and lessened visual acuity. Among these, only muscle strength is rel
iably enhanced with resistance exercise, which may aid in reducing hip frac
ture risk as well as improving the ability to undertake daily activities an
d maintain independence.