SYNDROME OF INAPPROPRIATE ADH SECRETION ATTRIBUTED TO THE SEROTONIN REUPTAKE INHIBITORS, VENLAFAXINE AND PAROXETINE

Authors
MEYNAAR IA PEETERS AJ MULDER AH OTTERVANGER JP
Citation
Ia. Meynaar et al., SYNDROME OF INAPPROPRIATE ADH SECRETION ATTRIBUTED TO THE SEROTONIN REUPTAKE INHIBITORS, VENLAFAXINE AND PAROXETINE, Netherlands journal of medicine, 50(6), 1997, pp. 243-245
Citations number
7
Categorie Soggetti
Medicine, General & Internal
Journal title
Netherlands journal of medicine → ACNP
ISSN journal
03002977
Volume
50
Issue
6
Year of publication
1997
Pages
243 - 245
Database
ISI
SICI code
0300-2977(1997)50:6<243:SOIASA>2.0.ZU;2-7
Abstract
We report on 2 patients with the syndrome of inappropriate secretion o f antidiuretic hormone (SIADH) which developed a few weeks after they had started treatment with venlafaxine and paroxetine, respectively. D ue to the temporal relationship and the exclusion of other potential c auses, a causal relationship between the use of the antidepressants an d SIADH seems likely. Diagnostic criteria for SIADH and the role of dr ugs, especially serotonin re-uptake inhibitors, are discussed. (C) 199 7 Elsevier Science B.V.