Heterocyclic systems containing bridged nitrogen atom: Synthesis and antibacterial activity of 3-(2-phenylquinolin-4-yl)/3-(1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-yl)-s-triazolo[3,4-b]-1,3,4-thiadiazine derivatives
Xp. Hui et al., Heterocyclic systems containing bridged nitrogen atom: Synthesis and antibacterial activity of 3-(2-phenylquinolin-4-yl)/3-(1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-yl)-s-triazolo[3,4-b]-1,3,4-thiadiazine derivatives, J CHIN CHEM, 47(5), 2000, pp. 1115-1119
The condensation of 4-amino-5-mercapto-3-(2-phenylquinolin-4-yl)/3-(1-p-chl
orophenyl-5-methyl-1,2,3-triazol-4-yl)-1,2,4-triazoles 1a-b with chloroacet
aldehyde 2a-b, omega -bromo-omega-(1H-1,2,4-triazol-1-yl)acetophenone 3a-b,
chloranil 4a-b, 2-bromocyclohexanone 5a-b, 2,4'-dibromoacetophenone 6a-b a
nd 2-bromo-6'-methoxy-2'-acetonaphthone 7a-b are described. The structures
of the compounds synthesized were confirmed by elemental analyses, IR, H-1
NMR and mass spectra. The antibacterial activities were also evaluated.