Mobile elements and the human genome

Citation
Etl. Prak et Hh. Kazazian, Mobile elements and the human genome, NAT REV GEN, 1(2), 2000, pp. 134-144
Citations number
123
Categorie Soggetti
Biology,"Molecular Biology & Genetics
Journal title
NATURE REVIEWS GENETICS
ISSN journal
14710056 → ACNP
Volume
1
Issue
2
Year of publication
2000
Pages
134 - 144
Database
ISI
SICI code
1471-0056(200011)1:2<134:MEATHG>2.0.ZU;2-L
Abstract
Genomic DNA is often thought of as the stable template of heredity, largely dormant and unchanging, apart from perhaps the occasional point mutation. But it has become increasingly clear that DNA is dynamic rather than static , being subjected to rearrangements, insertions and deletions. Much of this plasticity can be attributed to transposable elements and their genomic re latives.