Cadherins in embryonic and neural morphogenesis

Citation
U. Tepass et al., Cadherins in embryonic and neural morphogenesis, NAT REV MOL, 1(2), 2000, pp. 91-100
Citations number
96
Categorie Soggetti
Cell & Developmental Biology
Journal title
NATURE REVIEWS MOLECULAR CELL BIOLOGY
ISSN journal
14710072 → ACNP
Volume
1
Issue
2
Year of publication
2000
Pages
91 - 100
Database
ISI
SICI code
1471-0072(200011)1:2<91:CIEANM>2.0.ZU;2-W
Abstract
Cadherins not only maintain the structural integrity of cells and tissues b ut also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also co ntribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.