Ontogeny of PACAP immunoreactivity in extrinsic and intrinsic innervation of chicken gut

Citation
Ep. Salvi et al., Ontogeny of PACAP immunoreactivity in extrinsic and intrinsic innervation of chicken gut, PEPTIDES, 21(11), 2000, pp. 1703-1709
Citations number
38
Categorie Soggetti
Biochemistry & Biophysics
Journal title
PEPTIDES
ISSN journal
01969781 → ACNP
Volume
21
Issue
11
Year of publication
2000
Pages
1703 - 1709
Database
ISI
SICI code
0196-9781(200011)21:11<1703:OOPIIE>2.0.ZU;2-5
Abstract
An immunohistochemical study was conducted on the ontogeny of pituitary ade nylate cyclase-activating polypeptide-27 (PACAP) immunoreactive elements wi thin the extrinsic and intrinsic nerve supply of the chicken embryo gut. Th e first PACAP-immunoreactivity was detected in the extrinsic nerve supply a t E 4 within the pharyngeal region and the primary sympathetic chain. At E 5.5 it appeared in the vagus nerve, the spinal cord, the secondary sympathe tic chain, some perivascular plexuses and the Remak ganglion. In the intrin sic nerve supply, the first PACAP-immunoreactive elements were shown at E 4 .5-E 5 in the mesenchymal bud of the proventriculus/gizzard. Then they grad ually appeared also cranially and caudally both in myenteric and submucous plexuses. (C) 2000 Elsevier Science Inc. All rights reserved.