MITOGENIC STIMULATION OF BOVINE PERIPHERAL-BLOOD MONONUCLEAR-CELLS BYTHEILERIA-SERGENTI ANTIGEN AND INHIBITION BY ANTIBODY FROM EXPERIMENTALLY INFECTED CATTLE

Authors
YANAGISAWA K NIINUMA S IKEDA I KAMIYAMA T
Citation
K. Yanagisawa et al., MITOGENIC STIMULATION OF BOVINE PERIPHERAL-BLOOD MONONUCLEAR-CELLS BYTHEILERIA-SERGENTI ANTIGEN AND INHIBITION BY ANTIBODY FROM EXPERIMENTALLY INFECTED CATTLE, Veterinary parasitology, 71(1), 1997, pp. 53-58
Citations number
9
Categorie Soggetti
Parasitiology,"Veterinary Sciences
Journal title
Veterinary parasitology → ACNP
ISSN journal
03044017
Volume
71
Issue
1
Year of publication
1997
Pages
53 - 58
Database
ISI
SICI code
0304-4017(1997)71:1<53:MSOBPM>2.0.ZU;2-W
Abstract
Stimulation with a lysate of Theileria sergenti-parasitized red blood cells (PRBC) resulted in marked proliferation of normal bovine periphe ral blood mononuclear cells (PBMC) in vitro. partial inhibition of the proliferation was demonstrated by the addition of immunoglobulin (Ig) obtained from experimentally infected cattle when they revealed high levels of parasitemia and antibody titres. A mouse monoclonal antibody recognizing a 32 kDa antigen also showed inhibitory activity against the in vitro proliferation of bovine PBMC, but complete inhibition cou ld not be achieved. (C) 1997 Elsevier Science B.V.